Bogdan Wlodarczyk, Publications  

Hill D., Wlodarczyk B., Mitchell L., Finnell RH. Arsenate induced maternal hyperglycemia and neural tube defects in a mouse model. Toxicol. and Appl. Pharmacol. 2009 In Press.

Gray, R.S., Abitua, P.B., Wlodarczyk, B.J., Blanchard^, O., Lee, I., Weiss, G., Marcotte, E.M., Wallingford, J.B., and Finnell, R.H. The planar cell polarity effector protein Fuzzy is essential for targeted membrane trafficking, ciliogenesis, and mouse embryonic development. Nat. Cell Biol. 2009 In Press.

Pessah N., Bialer M., Wlodarczyk B., Finnell R., Yagen B. α-Fluoro-2,2,3,3-Tetramethylcyclopropanecarboxamide a Novel Potent Anticonvulsant Derivative of a Cyclic Analogue of Valproic Acid". Journal of Medical Chemistry 52(8): 2233-42, 2009.

Shimshoni JA, Yagen B, Pessah N, Wlodarczyk B, Finnell RH, Bialer M. Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: A potential for a second generation drug to valproic acid. Epilepsia 49(7): 1202- 12. 2008

Hill, D.S., Wlodarczyk, B., Finnell, R.H. Reproductive consequences of oral arsenate exposure during pregnancy in a mouse model. Birth Defects Res B Dev Reprod Toxicol. 83(1):40-47, 2008.

Wong RL., Wlodarczyk BJ., Min KS., Scott ML., Kartiko S., Yu W., Merriweather MY., Vogel P., Zambrowicz BP., Finnell RH. Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube. Hum. Mol. Genet. 17(4):587-601, 2008.

Zhu H., Cabrera R., Wlodarczyk BJ., Bozinov D., Wang D., Schwartz RJ., Finnell RH. Differentially expressed genes in embryonic cardiac tissues of mice lacking Folr1 gene activity. BMC Dev Biol. 7(1):128-133, 2007.

Shimshoni JA., Bialer M., Wlodarczyk B., Finnell RH., Yagen B. Potent Anticonvulsant Urea Derivatives of Constitutional Isomers of Valproic Acid. J Med Chem. 50(25):6419-6427, 2007.

Zhu H., Wlodarczyk B., Scott M., Yu W., Merriweather M., Gelineau-Van Waes J., Schwartz R., Finnell R. Cardiovascular abnormalities in Folr1 knockout mice and folate rescue. Birth Defects Research Part A: Clinical and Molecular Teratology 79(4): 257-68, 2007.

Sobol E., Yagen B., Lamb L.G., White H.S., Wlodarczyk B.J., Finnell R.H., Bialer M. Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide. Epilepsy Research 73: 75-84, 2007.

Sobol E., Yagen B., White H.S., Wilcox K.S., Lamb J.G., Pappo O., Wlodarczyk B.J., Finnell R.H., Bialer M. Preclinical Evaluation of 2,2,3,3-Tetramethyl-cyclopropanecarbonyl-urea a Novel, Second Generation to Valproic Acid, Antiepileptic Drug. Neuropharmacology 51: 933-946, 2006.

Wlodarczyk B.J., Cabrera R.M., Hill D.S., Bozinov D., Zhu H., Finnell R.H. Arsenic-induced gene expression changes in the neural tube of folate transport defective mouse embryos. Neurotoxicology 27(4):547-557, 2006.

Massa V., Wlodarczyk B., Giavini E., Finnell RH. Myo-Inositol enhances teratogenicity of valproic acid in the mouse. Birth Defect Research (Part A) 76(3): 200-204 2006.

Abdelrahim M., Ariazi E., Kim K., Khan S., Barhoumi R., Burghardt R., Liu S., Hill D., Finnell R., Wlodarczyk B., Jordan VC., Safe S. 3-Methylcholanthrene and Other Aryl Hydrocarbon Receptor Agonists Directly Activate Estrogen Receptor α. Cancer Research 66(4): 2459-2467, 2006.

Wlodarczyk B.J., Tang L.S., Triplett A., Aleman F., Finnell R.H. Spontaneous Neural Tube Defects in Splotch Mice Supplemented with Selected Micronutrients. Toxicology and Applied Pharmacology 213(1): 55-63, 2006

Tang L.S, Miranda R.C, Santillano D.R, Wlodarczyk B.J, Finnell R.H. Role of Folbp1 in the Regional Regulation of Apoptosis and Cell Proliferation in the Developing Neural Tube and Craniofacies. American Journal of Medical Genetics 135(1): 48-58, 2005.

Spiegelstein O., Gould A., Wlodarczyk B., Tsie M., Lu X., Le C., Troen A., Selhub J., Piedrahita J.A., Salbaum J.M., Kappen C., Melnyk S., James J., Finnell R.H. Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiences. Toxicology and Applied Pharmacology 203(1): 18-26, 2005.

Tang L.S, Wlodarczyk B.J, Santillano D.R, Miranda R.C, Finnell R.H. Developmental consequences of abnormal folate transport during murine heart morphogenesis. Birth Defects Res Part A Clin Mol Teratol. 70(7): 449-58, 2004.

Spiegelstein O., Cabrera R.M., Bozinov D., Wlodarczyk B., Finnell R.H. Folate-regulated changes in gene expression in the anterior neural tube of folate binding protein-1 (Folbp1)-deficient murine embryos. Neurochem Res. 29(6): 1105-1112, 2004.

Isoherranen N., Yagen B., Spiegelstein O., Finnell R.H., Merriweather M., Woodhead J.H., Wlodarczyk B., White H.S., Bialer M. Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice. British Journal of Pharmacology 139(4): 755-764, 2003.

Wlodarczyk B. Congenital defects of central nervous system - arsenic induced disruption in neural tube gene expression. Habilitation thesis. NVRI edition, 2002.

Minta M., Biernacki B., Wlodarczyk B. Fluorine toxicity in primary stem cell culture. In „Metabolism fluoru" T. Ogoński, D. Samujlo and Z. Machoy (eds.). PAM Szczecin: 166-173, 2002.

Finnell R.H., Spiegelstein O., Wlodarczyk B., Triplett A, Pogribny I.P., Melnyk S, James J.S. DNA methylation in folbp1 knockout mice supplemented with folinic acid during gestation. J Nutrition 132: 2457S-2461S, 2002.

Szprengier-Juszkiewicz T., Semeniuk S., Wlodarczyk B. Plasma kinetics and tissue residues of fenbendazole following oral administration to pigs. Bulletin of the Veterinary Institute in Pulawy vol. 46 (1): 119-125, 2002.

Finnell, R.H., Wlodarczyk, B., Spiegelstein, O., Triplett, A. & Gelineau-vanWaes, J. Folate transport abnormalities and congenital defects. In Milstein, S., Kapatos, G., Levine, R.A. & Shane, B., eds. Chemistry and Biology of Pteridines and Folates. Kluwer Academic Publishers, Norwich, MA pp. 637-642, 2001

Wlodarczyk B., Spiegelstein O., Gelineau-van Waes J.,  Vorce R.L., Lu X., Le Ch.X., Finnell R.H. Arsenic-Induced Congenital Malformations in Genetically Susceptible Folate Binding Protein-2 (Folbp2) Knockout Mice. Toxicology and Applied Pharmacology 177 (3): 238-246, 2001.

Wlodarczyk B., Biernacki B., Minta M. Teratogenic action of antiepileptic drug: 2-propylpentanoic acid - effects on rat and hamster embryos cultured in vitro. Ginekologia Polska 72 (12): 955-960, 2001.

Wlodarczyk B., Biernacki B., Minta M., Zmudzki J. Postimplantation whole embryo culture assay for hamsters: an alternative to rat and mouse. TheScientificWorld 1 227-234, 2001.

Biernacki B., Wlodarczyk B., Minta M. Evaluation of the developmental toxicity of gentamicin using postimplantation rat whole embryo culture. Bulletin of the Veterinary Institute in Pulawy vol. 45 (2): 347-352, 2001.

Barber R., Wlodarczyk B. and Kenyon J. High throughput screening of single nucleotide polymorphisms (SNPs) using the BESS-T&G Base Reader Kit and the ABI PRISM 3700 DNA sequencer. Epicentre Forum 7 (3):1-3, 2000.

Finnell R.H., Gelineau-van Waes J., Bennett G.D., Barber R.C., Wlodarczyk B., Show G.M., Lammer E.J., Piedrahita J.A., Eberwine J.H. Genetic basis of susceptibility to environmentally induced neural tube defects. Annales of the New York Academy of Sciences 919: 261-277, 2000

Eudy J.D., Spiegelstein O., Barber R.C., Wlodarczyk B., Talbot J., Finnell R.H. Identification and characterization of the human and mouse SLC19A3 gene: a novel member of the reduced folate family micronutrient transporter genes. Molecular Genetics and Metabolism 71(4): 581-90, 2000.

Bennett G.D., Wlodarczyk B., Calvin J.A., Craig J.C., Finnell R.H. Valproic acid-induced alterations in growth and neurotrophic factor gene expression in murine embryos. Reproductive Toxicology 14 (1): 1-11, 2000.

Biernacki B., Wlodarczyk B., Minta M. Effect of sodium valproate on rat embryo development in vitro. Bulletin of the Veterinary Institute in Pulawy 44 (2): 201-206, 2000.

Wlodarczyk B., Minta M., Biernacki B., Szkoda J., Żmudzki J. Selenium protection gaainst cadmium toxicity in hamster embryos. Polish Journal of Environmental Studies 9 (4): 323 - 327, 2000.

Wlodarczyk B., Biernacki B., Minta M., Żmudzki J. Hamster whole-embryo culture as a new in vitro model for teratogenicity testing. Polish Journal of Veterinary Science 2 (4): 149-153, 1999.

Finnell R.H., Bennett G.D., Mather G.G., Wlodarczyk B., Bajpai M., Levy R.H. Effect of stiripentol dose on phenytoin-induced teratogenesis in a mouse model. Reprod. Toxicol. 13 (2): 85-91, 1999.

Szkoda J., Minta M., Biernacki B., Wlodarczyk B. Fluorine concentration in maternal and fetal tissues of rodents after experimental exposure to sodium fluoride in drinking water. In "Fluorine and bioelements in biology and medicine". T. Ogoński, D. Samujlo and Z. Machoy (eds.). PAM Szczecin, pp. 89-94, 1998.

Minta M., Biernacki B., Wlodarczyk B. Prenatal toxicity of fluorine: summary results from studies on rodents. In: Fluorine and bioelements in biology and medicine. T. Ogoński, D. Samujlo and Z. Machoy (eds.). PAM Szczecin, pp. 33-39, 1998.

Minta M., Wlodarczyk B., Biernacki B., Szkoda J. Experimental embryotoxicology of fluorine. In: Biological risk caused by fluorine compounds. Z. Machoya and D. Samujlo (eds.). PAAM Szczecin, pp. 62-66, 1998.

Biernacki B., Wlodarczyk B., Minta M. Micrometric and morphological assessment of early stage rat embryos - application for in vitro teratology testing. Ginekologia Polska LXIX (12): 919-921, 1998.

Biernacki B., Wlodarczyk B., Minta M. Postimplantation rat embryo-culture. Preliminary study. Acta Poloniae Toxicologica 6 (2): 265-269, 1998.

Minta M., Wlodarczyk B., Biernacki B., Żmudzki J. Possibilities for the reduction of the number of animals in toxicological experiments. Med. Wet. 54 (10): 663-666, 1998.

Minta M., Biernacki B., Wlodarczyk B., Żmudzki J. Effect of a long-term action of small doses of sodium fluoride on pregnant female rats and their fetuses. Bulletin of the Veterinary Institute in Pulawy vol. 42, No. 1: 45-53, 1998.

Wlodarczyk B., Minta M., Biernacki B. Spermatotoxic effects of the fungicide benlate on the reproductive system in male hamsters. Acta Poloniae Toxicologica 5 (2): 141-148, 1997.

Minta M,. Wlodarczyk B., Biernacki B., Żmudzki J. Sodium fluoride and pregnancy. Effect on reproductive parameters in hamsters. .Acta Poloniae Toxicologica 5 (1): 55-61, 1997.

Biernacki B., Wlodarczyk B. Obtaining of postimplantation rat embryos for in vitro teratology examinations. Ginekologia Polska LXVIII, No 5b: 51-53, 1997.

Craig J.C., Eberwine J.H., Calvin J.A., Wlodarczyk B., Bennett G.D., Finnell R.H. Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology. Biochemical and Molecular Medicine, 60 (2): 81-91, 1997.

Finnel R.H., Wlodarczyk B., Craig J.C., Piedrahita H., Bennett G.D. Strain dependent alteration in the expression of folate pathway genes following teratogenic exposure to valproic acid in mouse model. American Journal of Medical Genetics, 70: 303-311, 1997.

Wlodarczyk B., Craig J.C., Bennett G.D., Calvin J.A., Finnell R.H. Valproic acid induced changes in gene expression during neurulation in mouse model. Teratology, 54 (6): 284-297, 1996.

Minta M., Wlodarczyk B. Toxicology of reproduction in view of alternative methods. Medycyna Pracy XLVII nr 5, suplement 6: 93-103, 1996.

Wlodarczyk B., Bennett G.D., Calvin J.A, Finnell R.H.  Arsenic- induced neural tube defects in mice: alteration in cell cycle gene expression. Reproductive Toxicology, 10: 447-454, 1996.

Bennett G.D., Amore B.M., Finnell R.H., Wlodarczyk B., Kalhorn T.F., Skiles G.L., Nelson S.D., Slattery J.T. Teretogenicity of carbamazepine-10, 11- epoxide and oxcarbazepine in the SWV mouse. Journal of Pharmacology and Experimental Therapeutics, 279: 1237-1242, 1996.

Wlodarczyk B., Bennett G.D., Calvin J.A., Craig J.C., Finnell R.H.  Arsenic-induced alterations in embryonic transcription factor gene expression: implications for abnormal neural development. Developmental Genetics 18: 306-315, 1996.

Minta M., Biernacki B., Wlodarczyk B. Effect of cadmium on the prenatal development of hamsters and rats. Bulletin of the Veterinary Institute in Pulawy vol. 40, No. 1: 31-39, 1996.

Minta M., Wlodarczyk B., Biernacki B., Szkoda J., Juszkiewicz T. Selenium embryotoxicity in hamster following exposure to sodium selenite. Actae Poloniae Toxicologica 3 (2): 134-138, 1995.

Minta M., Biernacki B., Wlodarczyk B. Prenatal toxicity of dimethoate in hamsters, rats and rabbits. Bulletin of the Veterinary Institute in Pulawy vol. 39, No. 2: 125-131, 1995.

Wlodarczyk B., Biernacki B., Minta M., Kozaczynski W., Juszkiewicz T. Male golden hamster in male reproductive toxicology testing: Assessment of protective activity of selenium in acute cadmium intoxication. Bulletin of Environmental Contamination and Toxicology 6 (54): 907-912, 1995.

Biernacki B., Wlodarczyk B., Minta M., Juszkiewicz T. The influence of cypermethrin on the pregnancy and prenatal development of rabbits. Med. Wet. 51 (1): 31-32, 1995. 

Minta M., Wlodarczyk B., Biernacki B. Modern prenatal toxicology research trends. Actae Poloniae Toxicologica, Supplement 1, Vol. 2:43-48, 1994.

Wlodarczyk B. Usefulness of male golden hamster in reproductive toxicology. Doctoral thesis 1993.

Juszkiewicz T., Minta M., Wlodarczyk B., Biernacki B, Żmudzki J. Studies on the embryotoxic and teratogenic effects of Tolpa peat preparation. Acta Poloniae Pharmaceutica, vol. 50, nr. 3: 383-388, 1993.

Minta M., Wlodarczyk B., Biernacki B. Experimental evaluation of chemicals for prenatal risks. Ginekologia Polska, Supp: 148-153, 1993.

Juszkiewicz T., Minta M., Biernacki B.,Wlodarczyk B. Effect of selenium on prenatal development in rats. Med. wet. 49 (5): 223-225, 1993.

Juszkiewicz T., Minta M., Wlodarczyk B., Biernacki B. Teratological evaluation of Ukrain in hamsters and rats. Drugs under Experimental and Clinical Research. vol. 18 (supp.): 23-29, 1992.

Juszkiewicz T., Minta M., Wlodarczyk B., Biernacki B., Zmudzki J. Studies on the embryotoxic and teratogenic effects of Tolpa torf preparation (TTP). Preclinical investigations on Tolpa torf preparation (TTP), monograph, Torf Corporation, Wroclaw 1992.

Wlodarczyk B., Biernacki B., Minta M. Spermatotoxicity of dimethoate in rabbits. Med. Wet. 48 (11): 512-514, 1992.

Juszkiewicz T., Wlodarczyk B., Minta M., Biernacki B. Spermatotoxicity of monensin and tiamulin in hamsters following their oral administration. Med. Wet. 48 (7): 322-323, 1992.

Juszkiewicz T., Minta M., Wlodarczyk B., Biernacki B. Effects of Monensin and Tiamulin administered separately or simultaneously to pregnant hamsters and rats. Med. Wet. 48 (6): 252-254, 1992.

Juszkiewicz T., Wlodarczyk B., Minta M., Biernacki B. Seasonal changes of reproductive indices in male hamsters and their relationship to the light-dark cycle. Bull. Vet. Inst. 35 : 31-37, 1992.

Juszkiewicz T., Niewiadowska A., Semeniuk S., Biernacki B., Wlodarczyk B. Tissue concentration of chloramphenicol in pigs after intramuscular injection of Detreomycin. Med. wet. 47 (2): 67-69, 1991.

Juszkiewicz T., Wlodarczyk B., Minta M., Biernacki B. Suitability of male golden hamsters for experimental reproductive pathology. Pat. Pol. 41 (3): 138-142, 1990.

Minta M., Biernacki B., Wlodarczyk B. The influence of 2,3 dimethylquinoxaline-1, 4-di-N-oxide on prenatal development in hamster, rat and rabbit. Med. wet. 45 (7): 397-400, 1989.

For other publications, see PubMed (search:  Wlodarczyk, Bogdan)